| Compound | Day | |||||||
| 1 | 3 | 5 | 8 | 10 | 11 | 15 | 17 | |
| Daunorubicin | 10.00 mg/kg Q4Dx3 | 20.00 mg/kg Q4Dx2 | ||||||
| Mean gross body weight (g) | 22.2 | 22.7 | 23.1 | 23.4 | 23.0 | 22.6 | 18.9 | 17.3 |
| Mean BW change (g) | 0.5 | 0.9 | 1.2 | 0.8 | 0.4 | −3.3 | −4.9 | |
| Mean BW change (%) | 2 | 4 | 5 | 4 | 2 | −15 | −22 | |
| Daunorubicin orotate | 12.43 mg/kg Q4Dx3 | 24.86 mg/kg Q4Dx2 | ||||||
| Mean gross body weight (g) | 22.2 | 22.3 | 22.8 | 22.9 | 23.4 | 23.7 | 21.4 | 20.2 |
| Mean BW change (g) | 0.1 | 0.6 | 0.7 | 1.2 | 1.5 | −0.8 | −2.0 | |
| Mean BW change (%) | 0 | 3 | 3 | 5 | 7 | −4 | −9 | |